BIO304 Structural Biology

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Course Code Course Title Weekly Hours* ECTS Weekly Class Schedule
T P
BIO304 Structural Biology 3 0 6
Prerequisite Junior Standing It is a prerequisite to

None

Lecturer Betul Akcesme Office Hours / Room / Phone
Tuesday:
12:00-13:00 confirm before coming
Wednesday:
12:00-13:00 confirm before coming
A F1.34
E-mail bakcesme@ius.edu.ba
Assistant Assistant E-mail
Course Objectives The course aims to provide the knowledge of the basic protein molecular architecture and then to connect it to the basic cellular processes like enzymatic activity, transport, and membrane functions.
Textbook Introduction to Protein Structure, Branden and Tooze
Additional Literature
  • Textbook of Structural Biology, Anders Liljas , Lars Liljas , Jure Piskur, Göran Lindblom,Poul Nissen and Morten Kjeldgaard
  • The Structures of Life-National Institutes of Health (Booklet)
  • Proteins Structure and Function, Whitford
  • Protein Structure and Function: From Sequence to Consequence, Gregory A. Petsko and Dagmar Ringe
Learning Outcomes After successful  completion of the course, the student will be able to:
    Teaching Methods Lecture presentations with powerpoint and class discussions. Visual materials are provided to better explain the concept. Students are responsible to do assignments based on the topics. Project and student presentations.
    Teaching Method Delivery Face-to-face Teaching Method Delivery Notes
    WEEK TOPIC REFERENCE
    Week 1 Introduction to Structural Biology and Protein Structure
    Week 2 Protein Structure Hierarchy and Alpha Domains
    Week 3 Beta Domains / Alpha& Beta Domains
    Week 4 Protein Folding & Flexibility
    Week 5 Protein Folding & Flexibility and Thermodynamics of folding
    Week 6 DNA structure and DNA binding proteins in prokaryotes
    Week 7 DNA recognition by eukaryotic transcription factors
    Week 8 Midterm Exam
    Week 9 Overview of structural bioinformatics
    Week 10 Membran Proteins
    Week 11 Viral proteins and immune response
    Week 12 Prediction, Engineering, and Design of Protein Structures I
    Week 13 Prediction, Engineering, and Design of Protein Structures II
    Week 14 Determination of Protein Structure
    Week 15 Presentations of the the projects
    Assessment Methods and Criteria Evaluation Tool Quantity Weight Alignment with LOs
    Final Exam 1 40
    Semester Evaluation Components
    Quizzes 2 10
    Interm 1 30
    Project&Presentation 1 15
    Assignments 3 5
    ***     ECTS Credit Calculation     ***
     Activity Hours Weeks Student Workload Hours Activity Hours Weeks Student Workload Hours
    Lecture hours 3 14 42 In-term exam 10 2 20
    Final 5 4 20 Assignments 2 3 6
    Quizzes 3 2 6 Home Study 4 14 56
            Total Workload Hours = 150
    *T= Teaching, P= Practice ECTS Credit = 6
    Course Academic Quality Assurance: Semester Student Survey Last Update Date: 02/11/2022

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