BIO315 Cell and Tissue Culture Engineering
BIO315 Cell and Tissue Culture Engineering
Syllabus | International University of Sarajevo - Last Update on Mar 03, 2026
Genetics and Bioengineering
Course Objectives
This course presents an overview of current approaches being used to control and manipulate mammalian cells for therapeutic and scientific purposes. - Main goal is to teach students on how to use living cells and tissues combined with genetic engineering tools that can be used to integrate and enhance applications in biomedicine and overall research in life sciences. - An additional aim of the course is to provide specific knowledge on scientific and technical aspects of growing tissues and organs, as well as broader understanding of the challenges of producing, storing, delivering and using tissue engineered products, and their ethical and regulatory issues.
Learning Outcomes
After successful completion of the course, the student will be able to:
Course Materials
Required Textbook
Ler D., Glamoclija U., Suljagic M; Introduction to Mammalian Cell Culture (2016) PERFECTA,
Additional Literature
Other teaching Materials providedTeaching Methods
Online lectures
Discussions
Labwork
Weekly Topics
| Week | Topic | Readings / References |
|---|---|---|
| 1 | Presentation of the Syllabus - Introduction of the Course | |
| 2 | Cell culture history and types of Cell cultures | |
| 3 | Cell culture requirements, biosafety, biohazards | |
| 4 | Mammalian cell culture categories and cellular environment | |
| 5 | Storage, cryopreservation and cell culture sourcing | |
| 6 | Culturing, subculturing, quantification | |
| 7 | MIDTERM EXAM | |
| 8 | Contamination assesment in cell culture | |
| 9 | Viability assays in cell culture | |
| 10 | Apoptosis and cell death measurement I | |
| 11 | Apoptosis and cell death measurement II | |
| 12 | Proliferation assays I | |
| 13 | Proliferation assays II | |
| 14 | Protein interactions in cell cultures | |
| 15 | COURSE Overview |
Course Schedule (All Sections)
Office Hours & Room
Assessment Methods and Criteria
Assessment Components
Final Exam
AI: Not AllowedAlignment with Learning Outcomes :
Laboratory Assignments
AI: Not AllowedAlignment with Learning Outcomes :
In-term Exam
AI: Not AllowedAlignment with Learning Outcomes :
IUS Grading System
| Grading Scale | IUS Grading System | IUS Coeff. | Letter (B&H) | Numerical (B&H) |
|---|---|---|---|---|
| 0 - 44 | F | 0 | F | 5 |
| 45 - 54 | E | 1 | ||
| 55 - 64 | C | 2 | E | 6 |
| 65 - 69 | C+ | 2.3 | D | 7 |
| 70 -74 | B- | 2.7 | ||
| 75 - 79 | B | 3 | C | 8 |
| 80 - 84 | B+ | 3.3 | ||
| 85 - 94 | A- | 3.7 | B | 9 |
| 95 - 100 | A | 4 | A | 10 |
Late Work Policy
Information about late submission policies will be shared during class and posted in this section. Please check back for official guidelines.
ECTS Credit Calculation
📚 Student Workload
This 6 ECTS credit course corresponds to 150 hours of total student workload, distributed as follows:
Lecture Hours
28 hours ⏳ (14 week × 2 h)
Lab Assignments
42 hours ⏳ (14 week × 3 h)
Home Study
60 hours ⏳ (15 week × 4 h)
In-term Exam Study
10 hours ⏳ (1 week × 10 h)
Final Exam Study
10 hours ⏳ (1 week × 10 h)
150 Total Workload Hours
6 ECTS Credits
Course Policies
Academic Integrity
All work submitted must be your own. Plagiarism, cheating, or any form of academic dishonesty will result in disciplinary action according to university policies. When in doubt about citation practices, consult the instructor.
Attendance Policy
Students are expected to adhere to the attendance requirements as outlined in the International University of Sarajevo Study Rules and Regulations. Excessive absences, whether excused or unexcused, may impact academic performance and eligibility for assessment. Mandatory sessions (e.g., labs, workshops) require attendance unless formally exempted. For detailed policies on absences, documentation, and penalties, please refer to the official university regulations.
Technology & AI Policy
Laptops/tablets may be used for note-taking only during lectures. Phones should be silenced and put away during all class sessions. Audio/video recording requires prior permission from the instructor.
Artificial Intelligence (AI) Usage: The use of AI tools (e.g., ChatGPT, Copilot, Gemini) varies by assessment component. Please refer to the AI usage indicator next to each assessment item in the Assessment Methods and Criteria section above. Submitting AI-generated content as your own work, where AI is not explicitly allowed, constitutes an academic integrity violation.
Communication Policy
All course-related communication should occur through official university channels (institutional email or SIS). Emails should include [BIO315] in the subject line.
Academic Quality Assurance Policy
Course Academic Quality Assurance is achieved through Semester Student Survey. At the end of each academic year, the institution of higher education is obliged to evaluate work of the academic staff, or the success of realization of the curricula.
Learning Tips
Be prepared to contribute thoughtfully during class discussions, labs, or collaborative work. Active participation deepens understanding and encourages critical thinking.
Complete assigned readings or prep materials before class. Take notes, highlight key ideas, and jot down questions. Aim to grasp core concepts and their applications—not just facts.
Use course frameworks or methodologies to analyze problems, case studies, or projects. Begin early to allow time for reflection and refinement. Seek feedback to improve your work.
Don’t hesitate to reach out when something is unclear. Use office hours, discussion boards, or peer networks to clarify concepts and stay on track.
Syllabus Last Updated on Mar 03, 2026 | International University of Sarajevo
Print Syllabus
Referencing Curricula Print this page
| Course Code | Course Title | Weekly Hours* | ECTS | Weekly Class Schedule | ||||||
| T | P | |||||||||
| BIO315 | Cell and Tissue Culture Engineering | 3 | 2 | 6 | Wed 09-12h | |||||
| Prerequisite | Junior Standing | It is a prerequisite to | - | |||||||
| Lecturer | Office Hours / Room / Phone | Currently not available |
||||||||
| Assistant | Assistant E-mail | |||||||||
| Course Objectives | This course presents an overview of current approaches being used to control and manipulate mammalian cells for therapeutic and scientific purposes. - Main goal is to teach students on how to use living cells and tissues combined with genetic engineering tools that can be used to integrate and enhance applications in biomedicine and overall research in life sciences. - An additional aim of the course is to provide specific knowledge on scientific and technical aspects of growing tissues and organs, as well as broader understanding of the challenges of producing, storing, delivering and using tissue engineered products, and their ethical and regulatory issues. |
|||||||||
| Textbook | Ler D., Glamoclija U., Suljagic M; Introduction to Mammalian Cell Culture (2016) PERFECTA, | |||||||||
| Additional Literature |
|
|||||||||
| Learning Outcomes | After successful completion of the course, the student will be able to: | |||||||||
| Teaching Methods | Online lectures, discussions, Labwork, | |||||||||
| Teaching Method Delivery | Online | Teaching Method Delivery Notes | ||||||||
| WEEK | TOPIC | REFERENCE | ||||||||
| Week 1 | Presentation of the Syllabus - Introduction of the Course | |||||||||
| Week 2 | Cell culture history and types of Cell cultures | |||||||||
| Week 3 | Cell culture requirements, biosafety, biohazards | |||||||||
| Week 4 | Mammalian cell culture categories and cellular environment | |||||||||
| Week 5 | Storage, cryopreservation and cell culture sourcing | |||||||||
| Week 6 | Culturing, subculturing, quantification | |||||||||
| Week 7 | MIDTERM EXAM | |||||||||
| Week 8 | Contamination assesment in cell culture | |||||||||
| Week 9 | Viability assays in cell culture | |||||||||
| Week 10 | Apoptosis and cell death measurement I | |||||||||
| Week 11 | Apoptosis and cell death measurement II | |||||||||
| Week 12 | Proliferation assays I | |||||||||
| Week 13 | Proliferation assays II | |||||||||
| Week 14 | Protein interactions in cell cultures | |||||||||
| Week 15 | COURSE Overview | |||||||||
| Assessment Methods and Criteria | Evaluation Tool | Quantity | Weight | Alignment with LOs | AI Usage |
| Final Exam | 1 | 40 | Not Allowed | ||
| Semester Evaluation Components | |||||
| Laboratory Assignments | 6 | 30 | Not Allowed | ||
| In-term Exam | 1 | 30 | Not Allowed | ||
| *** ECTS Credit Calculation *** | |||||
| Activity | Hours | Weeks | Student Workload Hours | Activity | Hours | Weeks | Student Workload Hours | |||
| Lecture Hours | 2 | 14 | 28 | Lab Assignments | 3 | 14 | 42 | |||
| Home Study | 4 | 15 | 60 | In-term Exam Study | 10 | 1 | 10 | |||
| Final Exam Study | 10 | 1 | 10 | |||||||
| Total Workload Hours = | 150 | |||||||||
| *T= Teaching, P= Practice | ECTS Credit = | 6 | ||||||||
| Course Academic Quality Assurance: Semester Student Survey | Last Update Date: 27/03/2026 | |||||||||
