Course Summary Course Objectives Learning Outcomes Course Materials Teaching Methods Weekly Topics Course Schedule Office Hours Assestment ECTS Calculation Course Policies Learning Tips Print Syllabi Download as PNG

BIO407 Protein Engineering

Syllabus   |  International University of Sarajevo  -  Last Update on Mar 03, 2026

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Genetics and Bioengineering

Spring 2025 - 2026 | 6 ECTS Credits | International University of Sarajevo

Academic Year
2025 - 2026
Semester
Spring
Course Code
BIO407
Weekly Hours
3 Teaching + 1 Practice
ECTS
6
Prerequisites
Senior Standing
Teaching Mode Delivery
Face-to-face
Prerequisite For
-
Teaching Mode Delivery Notes
-
Cycle
I Cycle
Prof. Jane Doe

Mohamed Ibrahim

Course Lecturer

Position
Full Professor Dr.
Email
mragab@ius.edu.ba
Phone
033 957 203
Assistant(s)
Ajla Tipura
Assistant E-mail
-

Course Objectives

"The course aims : - To enable students to Describe rational and combinatorial methods of protein engineering - To train students to critically analyse data and conclusions from the primary literature - To train students to formulate an original research plan for a specific protein engineering study and describe the advantages and limitations of the proposed research - To enable students to converse at an advanced level about current key topics of investigation in the field of protein engineering"

Learning Outcomes

After successful completion of the course, the student will be able to:

1
Modify a protein purification scheme to a specific application.
2
Understand the different systems of recombinant protein expression with advantages and disadvantages of each one.
3
Comprehend the difficulties in working with proteomics compare to genomics.
4
Gain thinking and analysis skills in protein biochemistry, Protein 3-D Structure and Protein folding.
5
Communication skills well be developed by encouraging student participating in discussion and asking questions.

Course Materials

Required Textbook

Protein Structure and Function 1e, Whiteford D -2008 Wiley.

Additional Literature
Introduction to Protein Science; Architecture, Function and Genomics, Arthur M. Lesk, 2006 - Oxford.

Teaching Methods

Class discussions with examples
Active tutorial sessions for engaged learning and continuous feedback on progress
Team assigments
Team projects that involve real data, computer analysis, summary, interpretation and reporting

Weekly Topics

This weekly planning is subject to change with advance notice.
Week Topic Readings / References
1 An introduction to protein - Structure and function Whiteford chapter 1
2 Amino Acids: the building blocks of Proteins Whiteford chapter 2
3 Amino Acids: the building blocks of Proteins Whiteford chapter 2
4 The three dimensional structure of Proteins Whiteford chapter 3
5 The three dimensional structure of Proteins Whiteford chapter 3
6 The structure and function for fibrous proteins Whiteford chapter 4
7 The structure and function for fibrous proteins Whiteford chapter 4
8 The structure and function for membrane proteins Whiteford chapter 5
9 The structure and function for membrane proteins Whiteford chapter 5
10 Protein expression, purification and characterization Whiteford chapter 9
11 Protein expression, purification and characterization Whiteford chapter 9
12 Protein expression, purification and characterization Whiteford chapter 9
13 Protein folding Whiteford chapter 11
14 Protein folding Whiteford chapter 11
15 Revision

Course Schedule (All Sections)

SectionTypeDay 1Venue 1Day 2Venue 2
BIO407.1 Course Monday 15:00 - 17:50 A F1.11 - -
BIO407.1 Tutorial Thursday 17:00 - 18:50 A F2.13 - -

Office Hours & Room

DayTimeOfficeNotes
Monday 12:00 - 15:00 A F1.14
Tuesday 10:00 - 12:00 A F1.14
Wednesday 10:00 - 12:00 A F1.14
Thursday 10:00 - 12:00 A F1.14
Friday 10:00 - 12:00 A F1.14

Assessment Methods and Criteria

Assessment Components

40%x1
Final Exam
AI: Not Allowed

Alignment with Learning Outcomes :  1  4

30%x1
In-term Exam
AI: Not Allowed

Alignment with Learning Outcomes :  1  2  3  5

10%x2
Presentation
AI: Not Allowed

Alignment with Learning Outcomes :  1  3  5  6

20%x2
Quiz
AI: Not Allowed

Alignment with Learning Outcomes :  1  2  4

IUS Grading System

Grading Scale IUS Grading System IUS Coeff. Letter (B&H) Numerical (B&H)
0 - 44 F 0 F 5
45 - 54 E 1
55 - 64 C 2 E 6
65 - 69 C+ 2.3 D 7
70 -74 B- 2.7
75 - 79 B 3 C 8
80 - 84 B+ 3.3
85 - 94 A- 3.7 B 9
95 - 100 A 4 A 10

IUS Grading System

Letter marks that do not affect student's CGPA:
  • "IP" – In progress is assigned for recording unfulfilled student obligations related to graduation project/thesis/dissertation and internship.
  • "S" – Satisfactory is assigned to a student who passed the examinations that are not numerically graded or whose written assignment has been accepted.
  • "U" – Unsatisfactory is assigned to a student who failed to pass the examinations that are not numerically graded.
  • "W" – Withdrawal signifies that student has withdrawn from the relevant course.
Additional letter mark that affects student's CGPA:

"N/A" – Not attending, and it is assigned to a student who is suspended from the course or who does not meet the minimal requirement for attendance on lectures or tutorials. The course lecturer must follow the attendance policy and assign "N/A" in each case of a student failing attendance.

Late Work Policy

Information about late submission policies will be shared during class and posted in this section. Please check back for official guidelines.

ECTS Credit Calculation

📚 Student Workload

This 6 ECTS credit course corresponds to 150 hours of total student workload, distributed as follows:

Lecture Hours

45 hours ⏳ (15 week × 3 h)

Assignments

10 hours ⏳ (2 week × 5 h)

Home Study

45 hours ⏳ (15 week × 3 h)

In-term Exam Study

15 hours ⏳ (1 week × 15 h)

Final Exam Study

15 hours ⏳ (1 week × 15 h)

Term Project/Presentation

20 hours ⏳ (2 week × 10 h)

150 Total Workload Hours

6 ECTS Credits


Course Policies

Academic Integrity

All work submitted must be your own. Plagiarism, cheating, or any form of academic dishonesty will result in disciplinary action according to university policies. When in doubt about citation practices, consult the instructor.

Attendance Policy

Students are expected to adhere to the attendance requirements as outlined in the International University of Sarajevo Study Rules and Regulations. Excessive absences, whether excused or unexcused, may impact academic performance and eligibility for assessment. Mandatory sessions (e.g., labs, workshops) require attendance unless formally exempted. For detailed policies on absences, documentation, and penalties, please refer to the official university regulations.

Technology & AI Policy

Laptops/tablets may be used for note-taking only during lectures. Phones should be silenced and put away during all class sessions. Audio/video recording requires prior permission from the instructor.

Artificial Intelligence (AI) Usage: The use of AI tools (e.g., ChatGPT, Copilot, Gemini) varies by assessment component. Please refer to the AI usage indicator next to each assessment item in the Assessment Methods and Criteria section above. Submitting AI-generated content as your own work, where AI is not explicitly allowed, constitutes an academic integrity violation.

Communication Policy

All course-related communication should occur through official university channels (institutional email or SIS). Emails should include [BIO407] in the subject line.

Academic Quality Assurance Policy

Course Academic Quality Assurance is achieved through Semester Student Survey. At the end of each academic year, the institution of higher education is obliged to evaluate work of the academic staff, or the success of realization of the curricula.

More info

Article 112: Evaluation of Work of the Academic Staff

  1. At the end of each academic year, the institution of higher education is obliged to evaluate work of the academic staff, or the success of realization of the curricula.
  2. Evaluation of work of each academic staff member is to be carried out in accordance with the Statute of the institution of higher education by the institution as well as by students.
  3. The institutions of higher education are obliged to carry out a students’ evaluation survey on the academic staff performance after the end of each semester, or after the completed teaching cycle for the subject taught.
  4. Evaluation must evaluate: lecture quality, student-academic staff interaction, correctness of communication, teacher’s attitudes towards students attending the teaching activities and at assessments, availability of suggested reading material, attendance and punctuality of the teacher, along with other criteria which are defined in the Statute.
  5. The institution of higher education by a specific act determines the procedure for evaluation of the academic staff performance, the content of survey forms, the manner of conducting the evaluation, grading criteria for the evaluation, as well as adequate measures for the academic staff who received negative evaluation for two consecutive years.
  6. The evaluation of the academic staff performance is an integral process of establishment the quality assurance system, or self-control and internal quality assurance.
  7. Results of the evaluation of the academic staff performance are to be adequately analyzed by the institution of higher education, and the decision of the head of the organizational unit about the employee’s work performance is an integral part of the personal file of each member of academic staff.

Learning Tips

Engage Actively

Be prepared to contribute thoughtfully during class discussions, labs, or collaborative work. Active participation deepens understanding and encourages critical thinking.

Read and Review Purposefully

Complete assigned readings or prep materials before class. Take notes, highlight key ideas, and jot down questions. Aim to grasp core concepts and their applications—not just facts.

Think Critically in Assignments

Use course frameworks or methodologies to analyze problems, case studies, or projects. Begin early to allow time for reflection and refinement. Seek feedback to improve your work.

Ask Questions Early

Don’t hesitate to reach out when something is unclear. Use office hours, discussion boards, or peer networks to clarify concepts and stay on track.

Course Academic Quality Assurance: Semester Student Survey

Syllabus Last Updated on Mar 03, 2026 | International University of Sarajevo

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Course Code Course Title Weekly Hours* ECTS Weekly Class Schedule
T P
BIO407 Protein Engineering 3 1 6 Tuesday 12:00 - 2:50
Prerequisite Senior Standing It is a prerequisite to -
Lecturer Mohamed Ibrahim Office Hours / Room / Phone
Monday:
12:00-15:00
Tuesday:
10:00-12:00
Wednesday:
10:00-12:00
Thursday:
10:00-12:00
Friday:
10:00-12:00
A F1.14 - 033 957 203
E-mail mragab@ius.edu.ba
Assistant Ajla Tipura Assistant E-mail
Course Objectives "The course aims :
- To enable students to Describe rational and combinatorial methods of protein engineering
- To train students to critically analyse data and conclusions from the primary literature
- To train students to formulate an original research plan for a specific protein engineering study and describe the advantages and limitations of the proposed research
- To enable students to converse at an advanced level about current key topics of investigation in the field of protein engineering"
Textbook Protein Structure and Function 1e, Whiteford D -2008 Wiley.
Additional Literature
  • Introduction to Protein Science; Architecture, Function and Genomics, Arthur M. Lesk, 2006 - Oxford.
Learning Outcomes After successful  completion of the course, the student will be able to:
  1. Modify a protein purification scheme to a specific application.
  2. Understand the different systems of recombinant protein expression with advantages and disadvantages of each one.
  3. Comprehend the difficulties in working with proteomics compare to genomics.
  4. Gain thinking and analysis skills in protein biochemistry, Protein 3-D Structure and Protein folding.
  5. Communication skills well be developed by encouraging student participating in discussion and asking questions.
Teaching Methods Class discussions with examples. Active tutorial sessions for engaged learning and continuous feedback on progress. Team assigments. Team projects that involve real data, computer analysis, summary, interpretation and reporting.
Teaching Method Delivery Face-to-face Teaching Method Delivery Notes
WEEK TOPIC REFERENCE
Week 1 An introduction to protein - Structure and function Whiteford chapter 1
Week 2 Amino Acids: the building blocks of Proteins Whiteford chapter 2
Week 3 Amino Acids: the building blocks of Proteins Whiteford chapter 2
Week 4 The three dimensional structure of Proteins Whiteford chapter 3
Week 5 The three dimensional structure of Proteins Whiteford chapter 3
Week 6 The structure and function for fibrous proteins Whiteford chapter 4
Week 7 The structure and function for fibrous proteins Whiteford chapter 4
Week 8 The structure and function for membrane proteins Whiteford chapter 5
Week 9 The structure and function for membrane proteins Whiteford chapter 5
Week 10 Protein expression, purification and characterization Whiteford chapter 9
Week 11 Protein expression, purification and characterization Whiteford chapter 9
Week 12 Protein expression, purification and characterization Whiteford chapter 9
Week 13 Protein folding Whiteford chapter 11
Week 14 Protein folding Whiteford chapter 11
Week 15 Revision
Assessment Methods and Criteria Evaluation Tool Quantity Weight Alignment with LOs AI Usage
Final Exam 1 40 1,4 Not Allowed
Semester Evaluation Components
In-term Exam 1 30 1,2,3,5 Not Allowed
Presentation 2 10 1,3,5,6 Not Allowed
Quiz 2 20 1,2,4 Not Allowed
***     ECTS Credit Calculation     ***
 Activity Hours Weeks Student Workload Hours Activity Hours Weeks Student Workload Hours
Lecture Hours 3 15 45 Assignments 5 2 10
Home Study 3 15 45
In-term Exam Study 15 1 15 Final Exam Study 15 1 15
Term Project/Presentation 10 2 20
        Total Workload Hours = 150
*T= Teaching, P= Practice ECTS Credit = 6
Course Academic Quality Assurance: Semester Student Survey Last Update Date: 13/03/2026

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