Course Summary Course Objectives Learning Outcomes Course Materials Teaching Methods Weekly Topics Course Schedule Office Hours Assestment ECTS Calculation Course Policies Learning Tips Print Syllabi Download as PNG

BIO417 Molecular Diagnostics

Syllabus   |  International University of Sarajevo  -  Last Update on Mar 03, 2026

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Genetics and Bioengineering

Spring 2021 - 2022 | 6 ECTS Credits | International University of Sarajevo

Academic Year
2021 - 2022
Semester
Spring
Course Code
BIO417
Weekly Hours
3 Teaching + 0 Practice
ECTS
6
Prerequisites
Senior Standing
Teaching Mode Delivery
Face-to-face
Prerequisite For
-
Teaching Mode Delivery Notes
-
Cycle
I Cycle
Prof. Jane Doe

Jasmin Šutković

Course Lecturer

Position
Associate Professor Dr.
Email
jsutkovic@ius.edu.ba
Phone
033 957 187
Assistant(s)
-
Assistant E-mail
-

Course Objectives

The main objective of the course in “Molecular Diagnostic” is to make the student familiar to the procedures used in a Laboratory of Molecular Diagnostics. The course will describe the techniques commonly used in diagnostics and molecular biology laboratories and the underlying principles and applications, advantages and limitations of each technique.

Learning Outcomes

After successful completion of the course, the student will be able to:

1
Define basic terminology and describe concepts in molecular diagnostics that provide the foundation for implementing and adapting new techniques and assays.
2
Explain the principle of nucleic acid isolation from blood and solid tissues, and how to store RNA and DNA for further analysis.
3
Explain and perform the polymerase chain reaction (PCR), reverse transcriptase PCR, and other amplification techniques.
4
Explain and perform electrophoresis and hybridization methods, including Southern and Northern blots.
5
Apply molecular diagnostic techniques in the diagnosis of microbiological, hematological, thrombotic, and genetic disorders.
6
Discuss ethical considerations of molecular test results, such as privacy and discrimination.

Course Materials

Required Textbook

Molecular Diagnostics - Fundamentals, Methods and Clinical Applications. Second edition. By Lela Buckingham-2012

Additional Literature
-

Teaching Methods

Lectures, literature exercise, and site visit
Participation in LABS, seminars and literature assignment is mandatory

Weekly Topics

This weekly planning is subject to change with advance notice.
Week Topic Readings / References
1 Introduction to syllabus - Biosafety in lab TBA
2 Fundamentals of Nucleic Acids Biochemistry- An overview Chapter 1-3
3 Common Techniques in Molecular Biology -Nucleic Acids extractions and quantification- Lab 1 Chapter 4-5
4 Common Techniques in Molecular Biolog - Protein isolation/Quantification/Western blot- Lab 2 Chapter 6
5 Common Techniques in Molecular Biolog - PCR methods - PCR Lab 3 Chapter 7
6 Common Techniques in Molecular Biolog - PCR methods - QPCR Lab 4 Chapter 8
7 Midterm exam
8 Common Techniques in Molecular Biolog - Chromosomal structure and mutations - Visit 1 TBA
9 Common Techniques in Molecular Biolog - Gene mutations and detection methods Chapter 9
10 Common Techniques in Molecular Biolog - Sequencing methods TBA
11 Techniques in Clinical laboratory 1 - DNA polymorphisms and Human identification -Visit 2 Chapter 11
12 Techniques in Clinical laboratory 2- Detection and identification of Microorganisms - Visit 3 Chapter 12
13 Techniques in Clinical laboratory 3 - Molecular basis of Cancer Chapter 14
14 Techniques in Clinical laboratory 4 - Quality assurance and control in the Mol. Biology lab Chapter 16
15 Review

Course Schedule (All Sections)

Course Schedules with all sections will be available here soon.

Office Hours & Room

DayTimeOfficeNotes
Tuesday 09:00 - 12:00 A F1.13 Or any time via teams
Thursday 09:00 - 11:00 A F1.13 Or any time via teams

Assessment Methods and Criteria

Assessment Components

35%x1
Final Exam/Project
AI: Not Allowed

Alignment with Learning Outcomes :  1  2  3  4

30%x1
Midterm Exam
AI: Not Allowed

Alignment with Learning Outcomes :  1  2  3  4

20%x5
Lab report/Assignments
AI: Not Allowed

Alignment with Learning Outcomes :  1  2

10%x1
Lab Activity/Review paper
AI: Not Allowed

Alignment with Learning Outcomes :  1  2

5%x1
Attecndance
AI: Not Allowed

Alignment with Learning Outcomes :  1  2  3  4  5  6

IUS Grading System

Grading Scale IUS Grading System IUS Coeff. Letter (B&H) Numerical (B&H)
0 - 44 F 0 F 5
45 - 54 E 1
55 - 64 C 2 E 6
65 - 69 C+ 2.3 D 7
70 -74 B- 2.7
75 - 79 B 3 C 8
80 - 84 B+ 3.3
85 - 94 A- 3.7 B 9
95 - 100 A 4 A 10

IUS Grading System

Letter marks that do not affect student's CGPA:
  • "IP" – In progress is assigned for recording unfulfilled student obligations related to graduation project/thesis/dissertation and internship.
  • "S" – Satisfactory is assigned to a student who passed the examinations that are not numerically graded or whose written assignment has been accepted.
  • "U" – Unsatisfactory is assigned to a student who failed to pass the examinations that are not numerically graded.
  • "W" – Withdrawal signifies that student has withdrawn from the relevant course.
Additional letter mark that affects student's CGPA:

"N/A" – Not attending, and it is assigned to a student who is suspended from the course or who does not meet the minimal requirement for attendance on lectures or tutorials. The course lecturer must follow the attendance policy and assign "N/A" in each case of a student failing attendance.

Late Work Policy

Information about late submission policies will be shared during class and posted in this section. Please check back for official guidelines.

ECTS Credit Calculation

📚 Student Workload

This 6 ECTS credit course corresponds to 150 hours of total student workload, distributed as follows:

Lab work

14 hours ⏳ (14 week × 1 h)

Final exam study

11 hours ⏳ (1 week × 11 h)

Lectures

28 hours ⏳ (14 week × 2 h)

Midterm preparation

20 hours ⏳ (2 week × 10 h)

Home study

77 hours ⏳ (11 week × 7 h)

150 Total Workload Hours

6 ECTS Credits


Course Policies

Academic Integrity

All work submitted must be your own. Plagiarism, cheating, or any form of academic dishonesty will result in disciplinary action according to university policies. When in doubt about citation practices, consult the instructor.

Attendance Policy

Students are expected to adhere to the attendance requirements as outlined in the International University of Sarajevo Study Rules and Regulations. Excessive absences, whether excused or unexcused, may impact academic performance and eligibility for assessment. Mandatory sessions (e.g., labs, workshops) require attendance unless formally exempted. For detailed policies on absences, documentation, and penalties, please refer to the official university regulations.

Technology & AI Policy

Laptops/tablets may be used for note-taking only during lectures. Phones should be silenced and put away during all class sessions. Audio/video recording requires prior permission from the instructor.

Artificial Intelligence (AI) Usage: The use of AI tools (e.g., ChatGPT, Copilot, Gemini) varies by assessment component. Please refer to the AI usage indicator next to each assessment item in the Assessment Methods and Criteria section above. Submitting AI-generated content as your own work, where AI is not explicitly allowed, constitutes an academic integrity violation.

Communication Policy

All course-related communication should occur through official university channels (institutional email or SIS). Emails should include [BIO417] in the subject line.

Academic Quality Assurance Policy

Course Academic Quality Assurance is achieved through Semester Student Survey. At the end of each academic year, the institution of higher education is obliged to evaluate work of the academic staff, or the success of realization of the curricula.

More info

Article 112: Evaluation of Work of the Academic Staff

  1. At the end of each academic year, the institution of higher education is obliged to evaluate work of the academic staff, or the success of realization of the curricula.
  2. Evaluation of work of each academic staff member is to be carried out in accordance with the Statute of the institution of higher education by the institution as well as by students.
  3. The institutions of higher education are obliged to carry out a students’ evaluation survey on the academic staff performance after the end of each semester, or after the completed teaching cycle for the subject taught.
  4. Evaluation must evaluate: lecture quality, student-academic staff interaction, correctness of communication, teacher’s attitudes towards students attending the teaching activities and at assessments, availability of suggested reading material, attendance and punctuality of the teacher, along with other criteria which are defined in the Statute.
  5. The institution of higher education by a specific act determines the procedure for evaluation of the academic staff performance, the content of survey forms, the manner of conducting the evaluation, grading criteria for the evaluation, as well as adequate measures for the academic staff who received negative evaluation for two consecutive years.
  6. The evaluation of the academic staff performance is an integral process of establishment the quality assurance system, or self-control and internal quality assurance.
  7. Results of the evaluation of the academic staff performance are to be adequately analyzed by the institution of higher education, and the decision of the head of the organizational unit about the employee’s work performance is an integral part of the personal file of each member of academic staff.

Learning Tips

Engage Actively

Be prepared to contribute thoughtfully during class discussions, labs, or collaborative work. Active participation deepens understanding and encourages critical thinking.

Read and Review Purposefully

Complete assigned readings or prep materials before class. Take notes, highlight key ideas, and jot down questions. Aim to grasp core concepts and their applications—not just facts.

Think Critically in Assignments

Use course frameworks or methodologies to analyze problems, case studies, or projects. Begin early to allow time for reflection and refinement. Seek feedback to improve your work.

Ask Questions Early

Don’t hesitate to reach out when something is unclear. Use office hours, discussion boards, or peer networks to clarify concepts and stay on track.

Course Academic Quality Assurance: Semester Student Survey

Syllabus Last Updated on Mar 03, 2026 | International University of Sarajevo

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Referencing Curricula Print this page

Course Code Course Title Weekly Hours* ECTS Weekly Class Schedule
T P
BIO417 Molecular Diagnostics 3 0 6 Mon: 15-17, Wed: 15-16
Prerequisite Senior Standing It is a prerequisite to -
Lecturer Jasmin Šutković Office Hours / Room / Phone
Tuesday:
9:00-12:00 Or any time via teams
Thursday:
9:00-11:00 Or any time via teams
A F1.13 - 033 957 187
E-mail jsutkovic@ius.edu.ba
Assistant Assistant E-mail
Course Objectives The main objective of the course in “Molecular Diagnostic” is to make the student familiar to the procedures used in a Laboratory of Molecular Diagnostics. The course will describe the techniques commonly used in diagnostics and molecular biology laboratories and the underlying principles and applications, advantages and limitations of each technique.
Textbook Molecular Diagnostics - Fundamentals, Methods and Clinical Applications. Second edition. By Lela Buckingham-2012
Additional Literature
  • -
Learning Outcomes After successful  completion of the course, the student will be able to:
  1. Define basic terminology and describe concepts in molecular diagnostics that provide the foundation for implementing and adapting new techniques and assays.
  2. Explain the principle of nucleic acid isolation from blood and solid tissues, and how to store RNA and DNA for further analysis.
  3. Explain and perform the polymerase chain reaction (PCR), reverse transcriptase PCR, and other amplification techniques.
  4. Explain and perform electrophoresis and hybridization methods, including Southern and Northern blots.
  5. Apply molecular diagnostic techniques in the diagnosis of microbiological, hematological, thrombotic, and genetic disorders.
  6. Discuss ethical considerations of molecular test results, such as privacy and discrimination.
Teaching Methods Lectures, literature exercise, and site visit. Participation in LABS, seminars and literature assignment is mandatory.
Teaching Method Delivery Face-to-face Teaching Method Delivery Notes
WEEK TOPIC REFERENCE
Week 1 Introduction to syllabus - Biosafety in lab TBA
Week 2 Fundamentals of Nucleic Acids Biochemistry- An overview Chapter 1-3
Week 3 Common Techniques in Molecular Biology -Nucleic Acids extractions and quantification- Lab 1 Chapter 4-5
Week 4 Common Techniques in Molecular Biolog - Protein isolation/Quantification/Western blot- Lab 2 Chapter 6
Week 5 Common Techniques in Molecular Biolog - PCR methods - PCR Lab 3 Chapter 7
Week 6 Common Techniques in Molecular Biolog - PCR methods - QPCR Lab 4 Chapter 8
Week 7 Midterm exam
Week 8 Common Techniques in Molecular Biolog - Chromosomal structure and mutations - Visit 1 TBA
Week 9 Common Techniques in Molecular Biolog - Gene mutations and detection methods Chapter 9
Week 10 Common Techniques in Molecular Biolog - Sequencing methods TBA
Week 11 Techniques in Clinical laboratory 1 - DNA polymorphisms and Human identification -Visit 2 Chapter 11
Week 12 Techniques in Clinical laboratory 2- Detection and identification of Microorganisms - Visit 3 Chapter 12
Week 13 Techniques in Clinical laboratory 3 - Molecular basis of Cancer Chapter 14
Week 14 Techniques in Clinical laboratory 4 - Quality assurance and control in the Mol. Biology lab Chapter 16
Week 15 Review
Assessment Methods and Criteria Evaluation Tool Quantity Weight Alignment with LOs AI Usage
Final Exam/Project 1 35 1,2,3,4 Not Allowed
Semester Evaluation Components
Midterm Exam 1 30 1,2,3,4 Not Allowed
Lab report/Assignments 5 20 1,2 Not Allowed
Lab Activity/Review paper 1 10 1,2 Not Allowed
Attecndance 1 5 1,2,3,4,5,6 Not Allowed
***     ECTS Credit Calculation     ***
 Activity Hours Weeks Student Workload Hours Activity Hours Weeks Student Workload Hours
Lab work 1 14 14 Final exam study 11 1 11
Lectures 2 14 28 Midterm preparation 10 2 20
Home study 7 11 77
        Total Workload Hours = 150
*T= Teaching, P= Practice ECTS Credit = 6
Course Academic Quality Assurance: Semester Student Survey Last Update Date: 27/03/2026

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