Course Summary Course Objectives Learning Outcomes Course Materials Teaching Methods Weekly Topics Course Schedule Office Hours Assestment ECTS Calculation Course Policies Learning Tips Print Syllabi Download as PNG

MED108 Medical Chemistry and Biochemistry II

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Medicine

Spring 2025 - 2026 | 6 ECTS Credits | International University of Sarajevo

Academic Year
2025 - 2026
Semester
Spring
Course Code
MED108
Weekly Hours
4 Teaching + 2 Practice
ECTS
6
Prerequisites
None
Teaching Mode Delivery
Face-to-face
Prerequisite For
-
Teaching Mode Delivery Notes
-
Cycle
I Cycle
Prof. Jane Doe

Irma Mahmuljin

Course Lecturer

Position
Assistant Professor Dr.
Email
imahmuljin@ius.edu.ba
Phone
033 957 -
Assistant(s)
Raneem Aldadah
Assistant E-mail
-

Course Objectives

This course aims to equip first-year medical students with the knowledge and practical skills to apply core chemical and biochemical principles to human system, explain structure–function relationships of biomolecules, analyze metabolic pathways and their rle in homeostatic and pathological conditions, integrate and predict metabolic flux across nutritional and physiological states, and interpret basic clinical biochemistry results—while safely performing fundamental laboratory techniques (solution preparation, buffer systems, spectrophotometry, and chromatography) and communicating findings with scientific rigor.

Learning Outcomes

After successful completion of the course, the student will be able to:

1
Apply principles of medical biochemistry and laboratory safety. Students will prepare samples and analyze according to the protocols and SOPs, and demonstrate laboratory safety/orientation practices during wet-lab sessions.
2
Analyze central bioenergetics with data. Integrate carbohydrate and lipid metabolism and predict flux changes. Students will estimate and interpret and trace energy flow through glycolysis, TCA cycle, electron transport & oxidative phosphorylation, including bioenergetics/biological oxidation. Students will compare and integrate PPP, fructose/galactose, glycogenesis/glycogenolysis/gluconeogenesis, fatty-acid synthesis/degradation, triglyceride/phospholipid, lipoprotein, and cholesterol metaboli
3
Analyze biochemical composition of different tissues. Students will explain the biochemistry of connective, nervous, bone tissues, and comprehend the mechanisms of muscle activities during resting and active states.
4
Interpret digestion of nutrients and enzymatic acticvity during the process. Students will explain the digestion of nutrients carbohydrates, proteins, lipids, their absorption and pathological condititons related to digestion; interpret case-based readouts from coagulation, blood/urinalysis/CSF, and endocrine-related biochemistry (e.g., fasting/feeding, tissue-specific biochemistry).
5
Interpret general characteristics of hormones and hormone action mechanisms. Students will explore endocrinology processes related to human systems, their impact in overall metabolism, regulation of systems activity and pathological conditions caused by environmental or genetic factors.

Course Materials

Required Textbook

Ronner P. Netter’s Essential Biochemistry. 1st ed. Elsevier; 2017. ISBN: 978-1929007639./Kennelly PJ, Botham KM, McGuinness OP, Rodwell VW, Weil PA. Harper’s Illustrated Biochemistry. 32nd ed. New York: McGraw Hill; 2023. ISBN (print): 978-1260469943; ISBN (eBook): 978-1260469950. Thomas M.Devlin, TEXTBOOK OF BIOCHEMISTRY WITH CLINICAL CORRELATIONS, Sixth Edition, Wiley-Liss publications

Additional Literature
Nelson DL, Cox MM. Lehninger Principles of Biochemistry. 7th ed. New York: W.H. Freeman; 2017. ISBN: 978-1319108243. / Champe PC, Harvey RA. Lippincott’s Illustrated Reviews: Biochemistry. 2nd ed. Philadelphia: J.B. Lippincott (Lippincott-Raven); 1994. ISBN: 978-0397510917. /

Teaching Methods

Interactive Lectures
Case-Based Learning
Short Video Demonstrations or Animations
Peer Teaching
Integration with Laboratory Content

Weekly Topics

This weekly planning is subject to change with advance notice.
Week Topic Readings / References
1 T: Bioenergetics and biological oxidation, Aerobic and anaerobic glycolysis, Citric acid cycle, Electron transport chain and oxidative phosphorylation, Pentose phosphate pathway, fructose and galactose metabolism Relevant Textbook Chapter
2 T: Glycogenesis, glycogenolysis, and gluconeogenesis, Fatty acid synthesis and degradation, Triglyceride and phospholipid metabolism, Cholesterol metabolism Relevant Textbook Chapter
3 T: Lipoprotein metabolism, Amino acid cycle, Special compounds derived from amino acids Relevant Textbook Chapter
4 T: Nucleic acid cycle, Alcohol metabolism, Biochemistry of fasting and feeding, Regulation of metabolism; P: Blood glucose level measurement with glucometer Relevant Textbook Chapter
5 QUIZ1; T: Biochemistry of connective tissue, Biochemistry of bone tissue; P: Blood glucose level measurement with glucometer Relevant Textbook Chapter
6 T: Biochemistry of muscle and exercise, P: Complete urine analysis part I Relevant Textbook Chapter
7 T:Biochemistry of nervous tissue, P: Complete urine analysis part II Relevant Textbook Chapter
8 Midterm Exam
9 T: Digestion and absorption of carbohydrates, Digestion and absorption of lipids, Digestion of proteins and absorption of amino acids Relevant Textbook Chapter
10 T: Metabolism of xenobiotics, Overview of metabolism, Plasma proteins and immunoglobulins, Iron metabolism, P: Analysys of blod plasma/serum proteins Relevant Textbook Chapter
11 T:QUIZ2; General characteristics of hormones, Hormone action mechanisms: Signal transduction, Pituitary and hypothalamic hormones, Thyroid hormones Relevant Textbook Chapter
12 T: Thyroid hormones, Hormones that regulate calcium metabolism, Pancreas and gastrointestinal system hormones Relevant Textbook Chapter
13 T: Adrenal Cortex Hormones, Eicosanoids, Adipocyte hormones Relevant Textbook Chapter
14 T: Adrenal Medulla Hormones, Overview of hormones; Guest lectures Relevant Textbook Chapter
15 T: Review of chapters/Seminars Relevant Textbook Chapter

Course Schedule (All Sections)

SectionTypeDay 1Venue 1Day 2Venue 2
MED108.1 Course Tuesday 14:00 - 16:50 B F1.22 - -
MED108.1 Tutorial Thursday 09:00 - 11:50 RC.G3 - GBE III - -

Office Hours & Room

DayTimeOfficeNotes
Thursday 14:00 - 15:30 A G.6

Assessment Methods and Criteria

Assessment Components

40%x1
Final Exam
AI: Not Allowed

Alignment with Learning Outcomes :  1  2  3  4  5

20%x1
Midterm Exam
AI: Not Allowed

Alignment with Learning Outcomes :  1  2  3

10%x4
Lab Tutorials and Reports
AI: Not Allowed

Alignment with Learning Outcomes :  1  2  3  4  5

10%x2
Quiz
AI: Not Allowed

Alignment with Learning Outcomes :  1  2  3  4  5

15%x1
Project
AI: Not Allowed

Alignment with Learning Outcomes :  3

5%x1
Attendance and Participation
AI: Not Allowed

Alignment with Learning Outcomes :  1  2  3  4  5

IUS Grading System

Grading Scale IUS Grading System IUS Coeff. Letter (B&H) Numerical (B&H)
0 - 44 F 0 F 5
45 - 54 E 1
55 - 64 C 2 E 6
65 - 69 C+ 2.3 D 7
70 -74 B- 2.7
75 - 79 B 3 C 8
80 - 84 B+ 3.3
85 - 94 A- 3.7 B 9
95 - 100 A 4 A 10

IUS Grading System

Letter marks that do not affect student's CGPA:
  • "IP" – In progress is assigned for recording unfulfilled student obligations related to graduation project/thesis/dissertation and internship.
  • "S" – Satisfactory is assigned to a student who passed the examinations that are not numerically graded or whose written assignment has been accepted.
  • "U" – Unsatisfactory is assigned to a student who failed to pass the examinations that are not numerically graded.
  • "W" – Withdrawal signifies that student has withdrawn from the relevant course.
Additional letter mark that affects student's CGPA:

"N/A" – Not attending, and it is assigned to a student who is suspended from the course or who does not meet the minimal requirement for attendance on lectures or tutorials. The course lecturer must follow the attendance policy and assign "N/A" in each case of a student failing attendance.

Late Work Policy

Information about late submission policies will be shared during class and posted in this section. Please check back for official guidelines.

ECTS Credit Calculation

📚 Student Workload

This 6 ECTS credit course corresponds to 150 hours of total student workload, distributed as follows:

Lecture Hours

56 hours ⏳ (14 week × 4 h)

Practical Lecture

12 hours ⏳ (4 week × 3 h)

Project

6 hours ⏳ (3 week × 2 h)

Lab Tutorials and Reports

8 hours ⏳ (4 week × 2 h)

Midterm Exam

24 hours ⏳ (6 week × 4 h)

Final Exam

32 hours ⏳ (8 week × 4 h)

Quiz

12 hours ⏳ (6 week × 2 h)

150 Total Workload Hours

6 ECTS Credits


Course Policies

Academic Integrity

All work submitted must be your own. Plagiarism, cheating, or any form of academic dishonesty will result in disciplinary action according to university policies. When in doubt about citation practices, consult the instructor.

Attendance Policy

Students are expected to adhere to the attendance requirements as outlined in the International University of Sarajevo Study Rules and Regulations. Excessive absences, whether excused or unexcused, may impact academic performance and eligibility for assessment. Mandatory sessions (e.g., labs, workshops) require attendance unless formally exempted. For detailed policies on absences, documentation, and penalties, please refer to the official university regulations.

Technology & AI Policy

Laptops/tablets may be used for note-taking only during lectures. Phones should be silenced and put away during all class sessions. Audio/video recording requires prior permission from the instructor.

Artificial Intelligence (AI) Usage: The use of AI tools (e.g., ChatGPT, Copilot, Gemini) varies by assessment component. Please refer to the AI usage indicator next to each assessment item in the Assessment Methods and Criteria section above. Submitting AI-generated content as your own work, where AI is not explicitly allowed, constitutes an academic integrity violation.

Communication Policy

All course-related communication should occur through official university channels (institutional email or SIS). Emails should include [MED108] in the subject line.

Academic Quality Assurance Policy

Course Academic Quality Assurance is achieved through Semester Student Survey. At the end of each academic year, the institution of higher education is obliged to evaluate work of the academic staff, or the success of realization of the curricula.

More info

Article 112: Evaluation of Work of the Academic Staff

  1. At the end of each academic year, the institution of higher education is obliged to evaluate work of the academic staff, or the success of realization of the curricula.
  2. Evaluation of work of each academic staff member is to be carried out in accordance with the Statute of the institution of higher education by the institution as well as by students.
  3. The institutions of higher education are obliged to carry out a students’ evaluation survey on the academic staff performance after the end of each semester, or after the completed teaching cycle for the subject taught.
  4. Evaluation must evaluate: lecture quality, student-academic staff interaction, correctness of communication, teacher’s attitudes towards students attending the teaching activities and at assessments, availability of suggested reading material, attendance and punctuality of the teacher, along with other criteria which are defined in the Statute.
  5. The institution of higher education by a specific act determines the procedure for evaluation of the academic staff performance, the content of survey forms, the manner of conducting the evaluation, grading criteria for the evaluation, as well as adequate measures for the academic staff who received negative evaluation for two consecutive years.
  6. The evaluation of the academic staff performance is an integral process of establishment the quality assurance system, or self-control and internal quality assurance.
  7. Results of the evaluation of the academic staff performance are to be adequately analyzed by the institution of higher education, and the decision of the head of the organizational unit about the employee’s work performance is an integral part of the personal file of each member of academic staff.

Learning Tips

Engage Actively

Be prepared to contribute thoughtfully during class discussions, labs, or collaborative work. Active participation deepens understanding and encourages critical thinking.

Read and Review Purposefully

Complete assigned readings or prep materials before class. Take notes, highlight key ideas, and jot down questions. Aim to grasp core concepts and their applications—not just facts.

Think Critically in Assignments

Use course frameworks or methodologies to analyze problems, case studies, or projects. Begin early to allow time for reflection and refinement. Seek feedback to improve your work.

Ask Questions Early

Don’t hesitate to reach out when something is unclear. Use office hours, discussion boards, or peer networks to clarify concepts and stay on track.

Course Academic Quality Assurance: Semester Student Survey

Syllabus Last Updated on Apr 04, 2026 | International University of Sarajevo

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Referencing Curricula Print this page

Course Code Course Title Weekly Hours* ECTS Weekly Class Schedule
T P
MED108 Medical Chemistry and Biochemistry II 4 2 6 Tuesday 14:00-16:50 and Thursday 9:00-11:50
Prerequisite None It is a prerequisite to -
Lecturer Irma Mahmuljin Office Hours / Room / Phone
Thursday:
14:00-15:30
A G.6
E-mail imahmuljin@ius.edu.ba
Assistant Raneem Aldadah Assistant E-mail
Course Objectives This course aims to equip first-year medical students with the knowledge and practical skills to apply core chemical and biochemical principles to human system, explain structure–function relationships of biomolecules, analyze metabolic pathways and their rle in homeostatic and pathological conditions, integrate and predict metabolic flux across nutritional and physiological states, and interpret basic clinical biochemistry results—while safely performing fundamental laboratory techniques (solution preparation, buffer systems, spectrophotometry, and chromatography) and communicating findings with scientific rigor.
Textbook Ronner P. Netter’s Essential Biochemistry. 1st ed. Elsevier; 2017. ISBN: 978-1929007639./Kennelly PJ, Botham KM, McGuinness OP, Rodwell VW, Weil PA. Harper’s Illustrated Biochemistry. 32nd ed. New York: McGraw Hill; 2023. ISBN (print): 978-1260469943; ISBN (eBook): 978-1260469950. Thomas M.Devlin, TEXTBOOK OF BIOCHEMISTRY WITH CLINICAL CORRELATIONS, Sixth Edition, Wiley-Liss publications
Additional Literature
  • Nelson DL, Cox MM. Lehninger Principles of Biochemistry. 7th ed. New York: W.H. Freeman; 2017. ISBN: 978-1319108243. / Champe PC, Harvey RA. Lippincott’s Illustrated Reviews: Biochemistry. 2nd ed. Philadelphia: J.B. Lippincott (Lippincott-Raven); 1994. ISBN: 978-0397510917. /
Learning Outcomes After successful  completion of the course, the student will be able to:
  1. Apply principles of medical biochemistry and laboratory safety. Students will prepare samples and analyze according to the protocols and SOPs, and demonstrate laboratory safety/orientation practices during wet-lab sessions.
  2. Analyze central bioenergetics with data. Integrate carbohydrate and lipid metabolism and predict flux changes. Students will estimate and interpret and trace energy flow through glycolysis, TCA cycle, electron transport & oxidative phosphorylation, including bioenergetics/biological oxidation. Students will compare and integrate PPP, fructose/galactose, glycogenesis/glycogenolysis/gluconeogenesis, fatty-acid synthesis/degradation, triglyceride/phospholipid, lipoprotein, and cholesterol metaboli
  3. Analyze biochemical composition of different tissues. Students will explain the biochemistry of connective, nervous, bone tissues, and comprehend the mechanisms of muscle activities during resting and active states.
  4. Interpret digestion of nutrients and enzymatic acticvity during the process. Students will explain the digestion of nutrients carbohydrates, proteins, lipids, their absorption and pathological condititons related to digestion; interpret case-based readouts from coagulation, blood/urinalysis/CSF, and endocrine-related biochemistry (e.g., fasting/feeding, tissue-specific biochemistry).
  5. Interpret general characteristics of hormones and hormone action mechanisms. Students will explore endocrinology processes related to human systems, their impact in overall metabolism, regulation of systems activity and pathological conditions caused by environmental or genetic factors.
Teaching Methods Interactive Lectures, Case-Based Learning, Short Video Demonstrations or Animations, Peer Teaching, Integration with Laboratory Content
Teaching Method Delivery Face-to-face Teaching Method Delivery Notes
WEEK TOPIC REFERENCE
Week 1 T: Bioenergetics and biological oxidation, Aerobic and anaerobic glycolysis, Citric acid cycle, Electron transport chain and oxidative phosphorylation, Pentose phosphate pathway, fructose and galactose metabolism Relevant Textbook Chapter
Week 2 T: Glycogenesis, glycogenolysis, and gluconeogenesis, Fatty acid synthesis and degradation, Triglyceride and phospholipid metabolism, Cholesterol metabolism Relevant Textbook Chapter
Week 3 T: Lipoprotein metabolism, Amino acid cycle, Special compounds derived from amino acids Relevant Textbook Chapter
Week 4 T: Nucleic acid cycle, Alcohol metabolism, Biochemistry of fasting and feeding, Regulation of metabolism; P: Blood glucose level measurement with glucometer Relevant Textbook Chapter
Week 5 QUIZ1; T: Biochemistry of connective tissue, Biochemistry of bone tissue; P: Blood glucose level measurement with glucometer Relevant Textbook Chapter
Week 6 T: Biochemistry of muscle and exercise, P: Complete urine analysis part I Relevant Textbook Chapter
Week 7 T:Biochemistry of nervous tissue, P: Complete urine analysis part II Relevant Textbook Chapter
Week 8 Midterm Exam
Week 9 T: Digestion and absorption of carbohydrates, Digestion and absorption of lipids, Digestion of proteins and absorption of amino acids Relevant Textbook Chapter
Week 10 T: Metabolism of xenobiotics, Overview of metabolism, Plasma proteins and immunoglobulins, Iron metabolism, P: Analysys of blod plasma/serum proteins Relevant Textbook Chapter
Week 11 T:QUIZ2; General characteristics of hormones, Hormone action mechanisms: Signal transduction, Pituitary and hypothalamic hormones, Thyroid hormones Relevant Textbook Chapter
Week 12 T: Thyroid hormones, Hormones that regulate calcium metabolism, Pancreas and gastrointestinal system hormones Relevant Textbook Chapter
Week 13 T: Adrenal Cortex Hormones, Eicosanoids, Adipocyte hormones Relevant Textbook Chapter
Week 14 T: Adrenal Medulla Hormones, Overview of hormones; Guest lectures Relevant Textbook Chapter
Week 15 T: Review of chapters/Seminars Relevant Textbook Chapter
Assessment Methods and Criteria Evaluation Tool Quantity Weight Alignment with LOs AI Usage
Final Exam 1 40 1,2,3,4,5 Not Allowed
Semester Evaluation Components
Midterm Exam 1 20 1,2,3 Not Allowed
Lab Tutorials and Reports 4 10 1,2,3,4,5 Not Allowed
Quiz 2 10 1,2,3,4,5 Not Allowed
Project 1 15 3 Not Allowed
Attendance and Participation 1 5 1,2,3,4,5 Not Allowed
***     ECTS Credit Calculation     ***
 Activity Hours Weeks Student Workload Hours Activity Hours Weeks Student Workload Hours
Lecture Hours 4 14 56 Practical Lecture 3 4 12
Project 2 3 6 Lab Tutorials and Reports 2 4 8
Midterm Exam 4 6 24 Final Exam 4 8 32
Quiz 2 6 12
        Total Workload Hours = 150
*T= Teaching, P= Practice ECTS Credit = 6
Course Academic Quality Assurance: Semester Student Survey Last Update Date: 08/04/2026

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